⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722910 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL772051 | 0.91 | GLA (0.45) | — | |
| SCHEMBL235080 | 0.85 | KDM4E (0.65) | — | |
| SCHEMBL231271 | 0.84 | KEAP1 (0.60) | — | |
| SCHEMBL5604233 | 0.84 | — | — | |
| SCHEMBL232859 | 0.82 | KEAP1 (0.58) | — | |
| SCHEMBL10913328 | 0.82 | KDM4E (0.70) | — | |
| SCHEMBL11856358 | 0.82 | KDM4E (0.70) | — | |
| SCHEMBL233216 | 0.80 | KEAP1 (0.56) | — | |
| SCHEMBL231245 | 0.80 | KEAP1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6886 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221577-A | 2-Phenoxyquinoline derivative, and preparation method and application thereof | 湖南中医药大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118146164-A | Hydrazone-containing quinazoline derivative or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 沈阳工业大学 | 2024-06-07 | — | — | CN | claimed |
| US-20240158397-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES THROUGH INHIBITON OF HSP90 | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2024-05-16 | — | — | US | claimed |
| CN-114450284-B | 6, 7-Dihydro-5H-pyrido [2,3-C ] pyridazine derivatives as BCL-XL protein inhibitors | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| CN-117843566-A | Polysubstituted benzene derivative, composition and use thereof | 康迈迪森(北京)医药科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| CN-116284021-B | Compounds having therapeutic effect on bladder cancer | 湖南大学 | 2024-04-02 | — | — | CN | claimed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | claimed |
| EP-4003989-B1 | 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER | SERVIER LAB (FR) | 2023-12-27 | — | — | EP | claimed |
| EP-0067019-B1 | NOVEL NITROSOUREA COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Kimura, Goro (JP) | 1986-03-19 | — | — | EP | claimed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | claimed |
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | claimed |
| US-4378358-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTIRHEUMATIC AGENTS | MEDIOLANUM FARMACEUTICI S.R.L. (IT) | 1983-03-29 | — | — | US | claimed |
| EP-0067019-A1 | Novel nitrosourea compound, method for preparing same, and pharmaceutical composition containing same | Kimura, Goro (JP) | 1982-12-15 | — | — | EP | claimed |
| EP-0004863-B1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS, TENSIOACTIVE CYCLIC POLYETHERS AND METHODS FOR PREPARING THEM | L'OREAL (FR) | 1982-06-16 | — | — | EP | claimed |
| EP-0043961-A1 | 1,2-Benzothiazinopyrazoles having pharmacological activity | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1982-01-20 | — | — | EP | claimed |
| US-4091219-A | ANTIINFLAMMATORY AGENTS, CNS DEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-05-23 | — | — | US | claimed |
| US-4057539-A | DYES, COLORFASTNESS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-11-08 | — | — | US | claimed |
| US-4009163-A | BACTERICIDES, FUNGICIDES | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | claimed |