Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327230 | 0.82 | TSHR (0.55) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL3037173 | 0.82 | TSHR (0.55) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL2480650 | 0.82 | TSHR (0.60) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL30261877 | 0.82 | ALDH1A1 (1.00) | TSHRALDH1A1TDP1HPGDMAPT | |
| SCHEMBL69613 | 0.82 | ALDH1A1 (1.00) | TSHRALDH1A1TDP1HPGDMAPT | |
| SCHEMBL69094 | 0.81 | TSHR (0.53) | TSHRALDH1A1GPR35TDP1MAPT | |
| SCHEMBL18224179 | 0.81 | ALDH1A1 (0.69) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL11693636 | 0.81 | ALDH1A1 (0.69) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL9723891 | 0.81 | TSHR (0.53) | TSHRALDH1A1GPR35TDP1HPGD | |
| SCHEMBL1167739 | 0.81 | TSHR (0.53) | TSHRALDH1A1GPR35TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240200070-A1 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2024-06-20 | — | — | US | disclosed |
| US-11814621-B2 | Expanding the chemical substrates for genetic code reprogramming | NORTHWESTERN UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230295613-A1 | LONG CHAIN CARBON AND CYCLIC AMINO ACIDS SUBSTRATES FOR GENETIC CODE REPROGRAMMING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2023-09-21 | — | — | US | disclosed |
| CN-109423309-B | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly | 奇美实业股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-115867648-A | Extension of chemical substrates for genetic code reprogramming to include long chain carbons and cyclic amino acids | 西北大学 | 2023-03-28 | — | — | CN | disclosed |
| EP-4103734-A2 | LONG CHAIN CARBON AND CYCLIC AMINO ACIDS SUBSTRATES FOR GENETIC CODE REPROGRAMMING | Northwestern University (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021221760-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS | NORTHWESTERN UNIVERSITY (US) | 2021-11-04 | — | — | WO | disclosed |
| US-20210230586-A1 | Expanding the Chemical Substrates for Genetic Code Reprogramming | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE | 2021-07-29 | — | — | US | disclosed |
| WO-2020128675-A1 | SUBSTITUTED 1,2,4-OXADIAZOLE, ITS APPLICATION AND A PHARMACEUTICAL PREPARATION COMPRISING IT | SVENOX PHARMACEUTICALS LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |
| EP-0723962-B1 | Arylalkyl-thiadiazinones | MERCK PATENT GMBH (DE) | 2001-07-04 | — | — | EP | disclosed |
| US-6025354-A | Arylalkyl-thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-15 | — | — | US | disclosed |
| US-5747489-A | Arylalkyl-thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |
| EP-0738715-A2 | Arylalkyl-pyridazinones | MERCK PATENT GmbH (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0723962-A1 | Arylalkyl-thiadiazinones | MERCK PATENT GmbH (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0452725-B1 | Fluorine containing diaminobenzene derivatives and its use | SAGAMI CHEM RES (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0635533-A1 | Polyimide-based liquid crystal aligning agent | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5153304-A | Polyimides; liquid crystal tilting agent; water-repelling | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5144078-A | Polyimide intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0452725-A2 | Fluorine containing diaminobenzene derivatives and its use | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-23 | — | — | EP | disclosed |