Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605096 | 0.87 | MAOA (0.55) | MAOBMAOALMNAMAPTRECQL | |
| SCHEMBL29214717 | 0.84 | CYP1A1 (0.55) | MAOBCYP1B1CXCL12 | |
| SCHEMBL498833 | 0.75 | MAPT (0.44) | MAOBMAOALMNAMAPTHPGD | |
| SCHEMBL498792 | 0.73 | MAOB (0.53) | MAOBMAOAMAPTCXCL12CXCR4 | |
| SCHEMBL7177488 | 0.73 | CYP3A4 (0.45) | MAOBLMNAMAPTHPGDNPC1 | |
| SCHEMBL11813928 | 0.73 | MAOB (0.58) | MAOBMAOALMNAMAPTHPGD | |
| SCHEMBL11813922 | 0.73 | MAOB (0.58) | MAOBMAOALMNAMAPTHPGD | |
| SCHEMBL8146123 | 0.72 | MAPT (0.59) | MAOBLMNAMAPTHPGDNPC1 | |
| SCHEMBL3969744 | 0.72 | CTSL (0.55) | MAOBMAPTABCG2CA1CA2 | |
| SCHEMBL498929 | 0.72 | ABCB1 (0.55) | MAOBMAOALMNAMAPTCXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525177-B1 | SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-06-27 | — | — | EP | claimed |