SCHEMBL5604419

SCHEMBL5604419

CC(C)Nc1cccc2c1C(=O)c1c(NC(C)C)cccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
MAPK1 P28482 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
EGFR P00533 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
PABPC1 P11940 1/20 0.59
RAB9A P51151 1/20 0.59
MAOA P21397 2/20 0.53
TERT O14746 7/20 0.46
ALDH1A1 P00352 3/20 0.44
LMNA P02545 3/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MALT1 Q9UDY8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9445880 0.94 MAPT (0.68) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL5605703 0.94 MAPT (0.61) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11523443 0.90 MAOA (0.62) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11525368 0.87 EGFR (0.54) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11523455 0.87 MAPT (0.55) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11528090 0.85 S100A4 (0.55) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11795891 0.84 MAOA (0.61) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL10810448 0.84 ADORA2A (0.61) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL1895554 0.84 MAPT (0.64) MAPTMAPK1TDP1SMN1; SMN2EGFR
SCHEMBL11797061 0.82 EGFR (0.55) MAPTMAPK1TDP1SMN1; SMN2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202292-B2 Colored polymeric resin composition with 1,8-diaminoanthraquinone derivative, article made therefrom, and method for making the same GENERAL ELECTRIC COMPANY (US) 2007-04-10 US claimed
US-7202292-B2 Colored polymeric resin composition with 1,8-diaminoanthraquinone derivative, article made therefrom, and method for making the same GENERAL ELECTRIC COMPANY (US) 2007-04-10 US disclosed
US-7087282-B2 Limited play optical storage medium, method for making the same GENERAL ELECTRIC COMPANY (US) 2006-08-08 US disclosed
EP-1647011-A1 LIMITED PLAY OPTICAL STORAGE MEDIUM, METHOD FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2006-04-19 EP disclosed
EP-1646682-A1 COLORED POLYMERIC RESIN COMPOSITION, ARTICLE MADE THEREFROM, AND METHOD FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2006-04-19 EP disclosed
WO-2005010090-A1 COLORED POLYMERIC RESIN COMPOSITION, ARTICLE MADE THEREFROM, AND METHOD FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2005-02-03 WO disclosed
WO-2005010872-A1 LIMITED PLAY OPTICAL STORAGE MEDIUM, METHOD FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2005-02-03 WO disclosed
US-20050014878-A1 Colored polymeric resin composition, article made therefrom, and method for making the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-01-20 US disclosed
US-20050013232-A1 Limited play optical storage medium, method for making the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-01-20 US disclosed