Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932620 | 0.86 | ALDH1A1 (0.38) | TP53THRBCHRM2GAA | |
| SCHEMBL20804462 | 0.84 | MEN1 (0.67) | MEN1KMT2ATDP1THRBMAOA | |
| SCHEMBL7625869 | 0.82 | HTT (0.63) | MEN1KMT2ATDP1TP53THRB | |
| SCHEMBL19064538 | 0.82 | MEN1 (0.48) | MEN1KMT2ATDP1TP53THRB | |
| SCHEMBL1654 | 0.81 | MEN1 (0.78) | MEN1KMT2ATDP1THRBMAOA | |
| SCHEMBL5799878 | 0.81 | MEN1 (0.78) | MEN1KMT2ATDP1THRBMAOA | |
| Benzene SCHEMBL11697595 | 0.81 | MEN1 (0.78) | MEN1KMT2ATDP1THRBMAOA | |
| O-Xylene SCHEMBL27958972 | 0.79 | MEN1 (0.61) | MEN1KMT2ATDP1TP53THRB | |
| SCHEMBL4497825 | 0.79 | HTT (0.55) | MEN1KMT2ATDP1TP53THRB | |
| SCHEMBL21550054 | 0.78 | MEN1 (0.74) | MEN1KMT2ATDP1THRBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390340-A4 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1390340-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |