SCHEMBL5604780

SCHEMBL5604780

COc1cc(Sc2ccc(Oc3cccc(N)c3)c(OC)c2)ccc1Oc1cccc(N)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
CYP3A4 P08684 2/20 0.51
MAOB P27338 1/20 0.46
DHFR P00374 1/20 0.43
AR P10275 2/20 0.43
MAPT P10636 3/20 0.41
POLB P06746 1/20 0.41
HSP90AA1 P07900 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TTR P02766 3/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
CYP19A1 P11511 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603440 0.83 ALDH1A1 (0.53) ALDH1A1CYP3A4MAOBDHFRMAPT
SCHEMBL8982092 0.83 CA12 (0.39) ALDH1A1CYP3A4DHFRMAPTSMN1; SMN2
SCHEMBL8904017 0.83 SMN1; SMN2 (0.45) ALDH1A1CYP3A4DHFRARMAPT
SCHEMBL632526 0.80 ALDH1A1 (0.62) ALDH1A1CYP3A4MAOBARMAPT
SCHEMBL5604090 0.80 MAOB (0.49) ALDH1A1CYP3A4MAOBDHFRMAPT
SCHEMBL8735764 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4MAOBARMAPT
SCHEMBL29436312 0.77 MAOB (0.64) ALDH1A1CYP3A4MAOBMAPTPOLB
SCHEMBL310158 0.77 MAOB (0.64) ALDH1A1CYP3A4MAOBMAPTPOLB
SCHEMBL125530 0.75 MAOB (0.68) ALDH1A1CYP3A4MAOBMAPTPOLB
SCHEMBL29363354 0.75 MAOB (0.68) ALDH1A1CYP3A4MAOBMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160949-B2 Olefin block copolymers, processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-01-09 US disclosed
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
US-20030055179-A1 Olefin block copolymers processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2003-03-20 US disclosed
EP-1275670-A1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-01-15 EP disclosed
EP-0738746-B1 Liquid crystal polyamide-imide copolymer MITSUI CHEMICALS INC (JP) 2002-07-24 EP disclosed
US-6307008-B1 CYCLIC TETRAACIDS WITH AROMATIC DIAMINES AS ADHESIVES FOR SEMICONDUCTORS AND ADHESIVES SAEHAN INDUSTRIES CORPORATION (KR) 2001-10-23 US disclosed
EP-0661347-B1 Polyimide resin composition having excellent fatigue resistance and injection molded article of same MITSUI CHEMICALS INC (JP) 2000-03-08 EP disclosed
EP-0605112-B1 Use of an insulating adhesive tape, lead frame and semiconductor device employing the tape MITSUI CHEMICALS INC (JP) 1999-03-17 EP disclosed
US-5821319-A COMPRISING STRUCTURAL UNITS DERIVED FROM PYROMELLITIC ANHYDRIDE, TEREPHTHALOYL CHLORIDE, 1,3-BIS/4-(4-AMINOPHENOXY)-ALPHA,ALPHA-DIMETHYLBENZYL/BENZENE MITSUI CHEMICALS, INC. (JP) 1998-10-13 US disclosed
EP-0633294-B1 Polyimide based resin composition MITSUI CHEMICALS INC (JP) 1998-06-10 EP disclosed
US-5087644-A Fibers coated with aromatic polyethersulfone and heated; high strength MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5043419-A Reacting an aromatic diamine, a tetracarboxylic dianhydride, and a dicarboxylic anhydride; molded products for air and space craft; heat resistant; mechanical strength MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-27 US disclosed
US-5041520-A Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-20 US disclosed
EP-0430640-A1 Polyimide based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-05 EP disclosed
US-5013817-A Monoamine reactant, melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0384712-A2 Carbon-fiber-reinforced polyimide resin compositions MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-29 EP disclosed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 US disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed