SCHEMBL5605064

SCHEMBL5605064

CNc1c(N)c2cccc3c(N)c(NC)c4cccc1c4c23

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
CYP3A4 P08684 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
LIMK1 P53667 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
HTR6 P50406 1/20 0.32
ACHE P22303 1/20 0.31
POLB P06746 1/20 0.31
NSD2 O96028 2/20 0.31
KEAP1 Q14145 3/20 0.30
NFE2L2 Q16236 2/20 0.30
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605384 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL18791708 0.79 KDM4E (0.52) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL20735847 0.77 CYP1A2 (0.51) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL5605522 0.74 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL27707225 0.74 KDM4E (0.34) ALDH1A1KDM4EMAPTHTR6KEAP1
SCHEMBL5605123 0.72 GAA (0.51) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL5605692 0.72 GAA (0.51) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL5518859 0.69 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL5515303 0.67 ALDH1A1 (0.35) ALDH1A1KDM4EMAPTCYP3A4HPGD
SCHEMBL8466087 0.67 TSHR (0.48) ALDH1A1KDM4EMAPTCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed