SCHEMBL5605522

SCHEMBL5605522

Nc1c(N)c2cccc3c(N)c(N)c4cccc1c4c23

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
HPGD P15428 6/20 0.50
HSD17B10 Q99714 5/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
HKDC1 Q2TB90 1/20 0.43
KEAP1 Q14145 2/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KDM4E B2RXH2 5/20 0.39
CASP1 P29466 3/20 0.39
GLA P06280 2/20 0.39
ACHE P22303 2/20 0.39
CASP7 P55210 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735488 0.82 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL29553771 0.82 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5604938 0.80 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5605700 0.80 PKM (0.40) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5605048 0.80 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5939928 0.80 PKM (0.40) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL743050 0.74 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL30561267 0.74 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL3289745 0.74 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5605384 0.74 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573484-B Organic electrode material, intermediate thereof, positive plate and battery 蜂巢能源科技股份有限公司 2023-06-20 CN claimed
CN-121824873-A Polymer-based tetraatom cluster electrocatalyst material, and preparation method and application thereof 武汉纺织大学 2026-04-10 CN disclosed
US-11976078-B2 Synthetically modifiable ion channels UNIVERSITY OF WYOMING (US) 2024-05-07 US disclosed
CN-114573484-B Organic electrode material, intermediate thereof, positive plate and battery 蜂巢能源科技股份有限公司 2023-06-20 CN disclosed
CN-114573484-A Organic electrode material, intermediate thereof, positive plate and battery 蜂巢能源科技股份有限公司 2022-06-03 CN disclosed
CN-114566611-A Electrode plate, preparation method thereof and secondary battery formed by electrode plate 蜂巢能源科技股份有限公司 2022-05-31 CN disclosed
US-20210230172-A1 SYNTHETICALLY MODIFIABLE ION CHANNELS UNIVERSITY OF WYOMING 2021-07-29 US disclosed
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11976078-B2 Synthetically modifiable ion channels KCNN2, KCNN1, HCN4 ALDH1A1 4727/4885HPGD 4262/4885HSD17B10 4719/4885
US-20210230172-A1 SYNTHETICALLY MODIFIABLE ION CHANNELS KCNN2, KCNN1, HCN4 ALDH1A1 4727/4885HPGD 4262/4885HSD17B10 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.