Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480545 | 0.86 | — | — | |
| SCHEMBL6541973 | 0.85 | ALDH1A1 (0.32) | ALDH1A1HPGDCYP3A4HSD17B10CYP1A1 | |
| SCHEMBL28470474 | 0.82 | ALDH1A1 (0.30) | ALDH1A1HPGDCYP3A4HSD17B10CYP1A1 | |
| SCHEMBL27683847 | 0.79 | KDM4E (0.42) | KDM4ECYP3A4HSD17B10LMNATP53 | |
| SCHEMBL1680608 | 0.79 | KDM4E (0.42) | KDM4ECYP3A4HSD17B10LMNATP53 | |
| SCHEMBL9719896 | 0.76 | — | — | |
| SCHEMBL27594499 | 0.76 | CA12 (0.32) | ALDH1A1HSD17B10HTR2ATSHR | |
| SCHEMBL27569298 | 0.76 | SIGMAR1 (0.35) | — | |
| SCHEMBL5534355 | 0.76 | — | — | |
| SCHEMBL28580710 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HPGDCYP3A4HSD17B10CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462470-B1 | Dielectric films and materials therefor | DAICEL CHEM (JP) | 2007-08-29 | — | — | EP | disclosed |