Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.75 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28761650 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL28518590 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL29101730 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL28090628 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Octane SCHEMBL9064774 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL28116168 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL21047520 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL21047518 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| Sulfuric Acid SCHEMBL20515715 | 0.95 | EPHX1 (0.75) | EPHX1CA1CA2PPARAS1PR2 | |
| SCHEMBL11607390 | 0.92 | EPHX1 (0.62) | EPHX1CA1CA2PPARAS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371389-C | Flame retardant aromatic polycarbonate resin composition | ASAHI CHEMICAL CORP (JP) | 2008-02-27 | — | — | CN | disclosed |
| US-7160937-B2 | Flame retardant aromatic polycarbonate resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-01-09 | — | — | US | disclosed |
| CN-1692141-A | Flame retardant aromatic polycarbonate resin composition | ASAHI CHEMICAL CORP (JP) | 2005-11-02 | — | — | CN | disclosed |
| US-20050154103-A1 | Blend with organic acid, sulfonic acid ester, or monomeric acid anhydride; alkali or alkaline earth metal salt carboxylate; and fluoropolymer; melt stability; heat, impact and aging resistance; waterproofing; injection and extrusion molding | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-07-14 | — | — | US | disclosed |