Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721635 | 0.87 | POLB (0.39) | POLBCA2CAMK2AALDH1A1HTT | |
| SCHEMBL28914492 | 0.76 | RXRA (0.35) | POLBCA2CAMK2AALDH1A1HTT | |
| SCHEMBL903597 | 0.76 | POLB (0.38) | POLBCA2CAMK2AHTTLMNA | |
| SCHEMBL11875776 | 0.73 | POLB (0.33) | POLBCA2CAMK2A | |
| SCHEMBL9444660 | 0.73 | POLB (0.33) | POLBCA2CAMK2A | |
| SCHEMBL29078656 | 0.72 | RXRA (0.35) | POLBRXRARXRBRXRG | |
| SCHEMBL30872107 | 0.71 | AKR1B1 (0.34) | POLBCA2AKR1B1 | |
| SCHEMBL30872113 | 0.71 | AKR1B1 (0.34) | POLBCA2AKR1B1 | |
| SCHEMBL28717676 | 0.71 | POLB (0.34) | POLBAKR1B1 | |
| SCHEMBL9781967 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745058-A1 | CYCLOOLEFIN PHOSPHINE LIGANDS AND THEIR USE IN CATALYSIS | Degussa GmbH (DE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005108407-A1 | CYCLOOLEFIN PHOSPHINE LIGANDS AND THEIR USE IN CATALYSIS | DEGUSSA AG (DE) | 2005-11-17 | — | — | WO | disclosed |