Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872107 | 1.00 | AKR1B1 (0.34) | AKR1B1POLBCXCL8CA2 | |
| SCHEMBL10721635 | 0.78 | POLB (0.39) | AKR1B1POLBCXCL8CA2 | |
| SCHEMBL28717676 | 0.73 | POLB (0.34) | AKR1B1POLB | |
| SCHEMBL9787156 | 0.72 | ALDH1A1 (0.40) | AKR1B1 | |
| SCHEMBL5605585 | 0.71 | POLB (0.36) | AKR1B1POLBCA2 | |
| SCHEMBL9444632 | 0.70 | SRC (0.30) | — | |
| SCHEMBL3469523 | 0.70 | RXRA (0.33) | CA2 | |
| SCHEMBL4649220 | 0.68 | RXRA (0.33) | — | |
| SCHEMBL903597 | 0.68 | POLB (0.38) | AKR1B1POLBCA2 | |
| SCHEMBL28914492 | 0.68 | RXRA (0.35) | POLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109688-A1 | PYRROLE FUSED RING DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 成都百裕制药股份有限公司 | 2024-05-30 | — | — | WO | disclosed |