Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 5/20 | 0.49 |
| ▸ | RXRB | P28702 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606050 | 0.85 | TSHR (0.51) | ALDH1A1CYP2D6HRH3TSHRMAOA | |
| SCHEMBL8133937 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RXRARXRBPLA2G4BNR4A2 | |
| SCHEMBL1749934 | 0.82 | ALDH1A1 (0.57) | ALDH1A1RXRARXRBTSHRPLA2G4B | |
| SCHEMBL27945814 | 0.81 | PLA2G4B (0.52) | ALDH1A1CYP2D6TSHRPLA2G4BLMNA | |
| SCHEMBL2431466 | 0.80 | CYP1A2 (0.56) | ALDH1A1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL1750568 | 0.79 | PLA2G4B (0.63) | ALDH1A1RXRARXRBTSHRPLA2G4B | |
| SCHEMBL1348061 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7057892 | 0.78 | AGXT (0.44) | ALDH1A1CYP2D6POLBKDM4ECYP1A2 | |
| SCHEMBL1749635 | 0.78 | ALDH1A1 (0.61) | ALDH1A1RXRARXRBPLA2G4BNR4A2 | |
| SCHEMBL250102 | 0.78 | EBP (0.69) | CYP2D6HRH3TSHRPLA2G4BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100543032-C | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2009-09-23 | — | — | CN | disclosed |
| CN-1961878-A | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA SA (FR) | 2007-05-16 | — | — | CN | disclosed |
| US-7166594-B2 | Antibacterial activity | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | disclosed |
| EP-1187847-B1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-12-03 | — | — | EP | disclosed |
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. | 2003-08-07 | — | — | US | disclosed |
| US-6569854-B1 | Virginamycins | AVENTIS PHARMA S.A. (FR) | 2003-05-27 | — | — | US | disclosed |
| CN-1358194-A | Streptogramin derivatives, preparation method and compositions containing them | AVETIS PHARMA S A (FR) | 2002-07-10 | — | — | CN | disclosed |
| EP-1187847-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001002427-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | MRPL21, ABHD5, APEH | ALDH1A1 4296/4885RXRA 1215/4885RXRB 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.