ABHD5 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL20846	1.00	2/20
SCHEMBL22146	1.00	2/20
Menadione (SCHEMBL25970)	1.00	2/20
SCHEMBL28181	1.00	2/20
SCHEMBL478244	1.00	2/20
SCHEMBL5111	0.95	2/20
SCHEMBL9619	0.95	2/20
SCHEMBL19685	0.95	2/20
SCHEMBL97495	0.95	2/20
SCHEMBL97496	0.95	2/20
SCHEMBL155137	0.95	2/20
SCHEMBL187662	0.95	2/20
SCHEMBL509571	0.95	2/20
SCHEMBL546046	0.95	2/20
SCHEMBL546073	0.95	2/20
Water (SCHEMBL424880)	0.86	2/20
Chloroform (SCHEMBL84057)	0.79	2/20
SCHEMBL184544	0.75	2/20
Cinnamic Acid (SCHEMBL1332)	0.73	2/20
Cinnamic Acid (SCHEMBL1333)	0.73	2/20

Clinical trials — most relevant to ABHD5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Omega 3 and Ischemic Stroke; Fish Oil as an Option	PHASE4	UNKNOWN
Effects of Omega-3 Fatty Acids on the Human Gene Expression	PHASE4	COMPLETED
Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris	PHASE1/PHASE2	UNKNOWN
Cholic Acid for Hepatic Steatosis in Lipodystrophy	PHASE2	COMPLETED
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Choline Effects - Pre-symptomatic AD	PHASE1	COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins	EARLY_PHASE1	RECRUITING
RCDP Natural History Study	nan	UNKNOWN
A 12 Week, 3-Period Study to Evaluate the Effects of a Dietary Supplement on Lipid Metabolism	nan	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Evaluation of Botanicals for Mechanisms Related to Appetite and Fat Metabolism	nan	COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity.	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients	nan	COMPLETED
Genetic Determinants:Low HDL, High Triglycerides, Obesity	nan	COMPLETED
Genetic and Environmental Determinants of Triglycerides (GOLDN)	nan	COMPLETED
The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.	nan	COMPLETED
Genomic Dissection of a QTL Affecting the Lipid Profile	nan	WITHDRAWN
Epidemiology of Atherosclerosis	nan	COMPLETED
A Prospective Study of the Disease Characteristics of Adult Patients With Long Chain Fatty Acid Oxidation Disorders	nan	COMPLETED
Genetic Origin of Lipid Disorders	nan	UNKNOWN
Role of Dairy Products in Weight Maintenance	nan	COMPLETED
Choline to Improve Malnutrition and Enhance Cognition	nan	RECRUITING
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing	nan	COMPLETED
Familial Partial Lipodystrophy Study	nan	COMPLETED
Tissue Lipids and Insulin Resistance	nan	WITHDRAWN

Related proteins — ESM-2 sequence neighbours (a ABHD5 binder may also engage these)

Protein	Name	Similarity
Q5RBI4	—	1.000	Q5RBI4 →
Q9DBL9	—	1.000	Q9DBL9 →
Q5EE05	—	1.000	Q5EE05 →
Q8TB40	—	1.000	Q8TB40 →
Q6QA69	—	0.999	Q6QA69 →
Q8VD66	—	0.998	Q8VD66 →
Q5EA59	—	0.997	Q5EA59 →
O02218	—	0.987	O02218 →
Q5PPS7	—	0.984	Q5PPS7 →
Q6GLL2	—	0.983	Q6GLL2 →
Q9ZUN1	—	0.982	Q9ZUN1 →
Q9LW26	—	0.982	Q9LW26 →
Q8R2Y0	—	0.981	Q8R2Y0 →
O14249	—	0.981	O14249 →
Q940H7	—	0.981	Q940H7 →
Q1LZ86	—	0.981	Q1LZ86 →
Q9ZVN2	—	0.981	Q9ZVN2 →
Q9FVW3	—	0.981	Q9FVW3 →
P0DKC5	—	0.981	P0DKC5 →
P0DKC6	—	0.981	P0DKC6 →
O18391	—	0.980	O18391 →
ABHD6	Monoacylglycerol lipase ABHD6	0.980	landscape →
Q7SY73	—	0.980	Q7SY73 →
Q9LHS7	—	0.980	Q9LHS7 →
Q5HZX7	—	0.980	Q5HZX7 →
Q6DHN0	—	0.980	Q6DHN0 →
Q9ASU8	—	0.980	Q9ASU8 →
P91143	—	0.980	P91143 →
Q0IIS3	—	0.980	Q0IIS3 →
O74430	—	0.979	O74430 →