Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5972792 | 0.83 | PKM (0.48) | ESR1ESR2SLC6A2SLC6A3LMNA | |
| SCHEMBL5972797 | 0.82 | PKM (0.47) | ESR1ESR2SLC6A2SLC6A3LMNA | |
| Hydrochloric Acid SCHEMBL8000443 | 0.82 | MAOB (0.59) | ESR1ESR2SLC6A2SLC6A3LMNA | |
| SCHEMBL6553509 | 0.81 | MAOB (0.54) | ESR1ESR2SLC6A2SLC6A3LMNA | |
| SCHEMBL6059951 | 0.79 | SLC6A2 (0.73) | ESR1ESR2SLC6A2SLC6A3LMNA | |
| SCHEMBL5605698 | 0.79 | PKM (0.44) | PKMALDH1A1KDM4EMEN1GAA | |
| SCHEMBL4993768 | 0.79 | PKM (0.46) | PKMALDH1A1KDM4EMEN1GAA | |
| SCHEMBL4999957 | 0.79 | F2 (0.72) | F2 | |
| SCHEMBL31506335 | 0.79 | F2 (0.72) | F2 | |
| SCHEMBL13140115 | 0.79 | F2 (0.53) | ESR1ESR2SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572179-B1 | PHARMACEUTICAL COMPOSITION COMPRISING A LTB4 ANTAGONIST AND A COX-2 INHIBITOR OR A COMBINED COX1/2 INHIBITOR | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1572179-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LTB4 ANTAGONIST AND A COX-2 INHIBITOR OR A COMBINED COX1/2 INHIBITOR | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-20040116516-A1 | Pharmaceutical composition | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-17 | — | — | US | disclosed |
| WO-2004047824-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LTB4 ANTAGONIST AND A COX-2 INHIBITOR OR A COMBINED COX1/2 INHIBITOR | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-10 | — | — | WO | disclosed |