Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 12/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005112 | 0.84 | PKM (0.41) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL10005110 | 0.84 | PKM (0.41) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL4993768 | 0.83 | PKM (0.46) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5972792 | 0.81 | PKM (0.48) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5972797 | 0.81 | PKM (0.47) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL668004 | 0.79 | PKM (0.44) | PKMKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5605671 | 0.79 | ESR1 (0.45) | PKMKDM4EMEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8000443 | 0.76 | MAOB (0.59) | MAOBF2 | |
| SCHEMBL4999957 | 0.75 | F2 (0.72) | F2 | |
| SCHEMBL31506335 | 0.75 | F2 (0.72) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773396-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND PAIN USING A COMBINATION OF A COX-2 SELECTIVE INHIBITOR AND A LTB4 RECEPTOR ANTAGONIST | Pharmacia Corporation (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006011048-A1 | COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND PAIN USING A COMBINATION OF A COX-2 SELECTIVE INHIBITOR AND A LTB4 RECEPTOR ANTAGONIST | PHARMACIA CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |