Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477876 | 0.81 | LMNA (0.49) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL9788809 | 0.81 | LMNA (0.49) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL27776493 | 0.81 | LMNA (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL522599 | 0.80 | LMNA (0.46) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL29770503 | 0.78 | NPC1 (0.46) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL7543000 | 0.76 | LMNA (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL7493232 | 0.76 | LMNA (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL8393240 | 0.75 | NPC1 (0.44) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL8395224 | 0.75 | NPC1 (0.44) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL14784613 | 0.75 | RAB9A (0.44) | LMNACYP1A2CYP2D6SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203616-B1 | CHIRAL LEAD CATALYST AND METHOD OF ASYMMETRIC ALDOL REACTION | JAPAN SCIENCE & TECH AGENCY (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-6780812-B2 | SUCH AS LEAD TRIFLATE AND A CHIRAL CROWN ETHER COMPOUND | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-08-24 | — | — | US | disclosed |
| EP-1203616-A1 | CHIRAL LEAD CATALYST AND METHOD OF ASYMMETRIC ALDOL REACTION | Japan Science and Technology Corporation (JP) | 2002-05-08 | — | — | EP | disclosed |