SCHEMBL5605848

SCHEMBL5605848

Cc1cccc(P(=O)(O)c2ccccc2)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA5A P35218 1/20 0.43
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.41
CFTR P13569 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ACP3 P15309 1/20 0.39
TRPA1 O75762 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
ATM Q13315 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
ALOX15 P16050 1/20 0.37
ESR1 P03372 1/20 0.37
MAPT P10636 1/20 0.37
AKR1B10 O60218 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2473967 0.86 CA2 (0.48) CA2CA4CA5ATSHRLMNA
SCHEMBL30598263 0.86 CA2 (0.48) CA2CA4CA5ATSHRLMNA
SCHEMBL497566 0.86 TRPA1 (0.44) CA2TSHRLMNAACP3TRPA1
SCHEMBL10431511 0.81 NPSR1 (0.49) CA2CA4CA5ALMNANPSR1
SCHEMBL28388314 0.80 CA2 (0.42) CA2CA4CA5ATSHRLMNA
SCHEMBL17223190 0.79 CA2 (0.48) CA2CA4CA5ATSHRLMNA
SCHEMBL29688212 0.78 ATM (0.44) CA2CA4CA5ATSHRLMNA
SCHEMBL125243 0.78 ATM (0.44) CA2CA4CA5ATSHRLMNA
SCHEMBL3787009 0.74 ESR1 (0.54) CA2CA4CA5ATSHRCFTR
SCHEMBL30085199 0.74 ESR1 (0.54) CA2CA4CA5ATSHRCFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670860-B1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORP (US) 2007-04-04 EP disclosed
US-20050075024-A1 Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability ALBEMARLE CORPORATION 2005-04-07 US disclosed