Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780133 | 0.79 | THRB (0.51) | THRB | |
| SCHEMBL28953664 | 0.78 | THRB (0.43) | THRBTHRAALDH1A1TGM2 | |
| SCHEMBL106694 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL108298 | 0.75 | TSHR (0.34) | — | |
| SCHEMBL22344272 | 0.74 | TSHR (0.41) | THRBALDH1A1 | |
| SCHEMBL6263247 | 0.73 | MAPT (0.42) | THRBHCAR2ALDH1A1TGM2 | |
| SCHEMBL20504448 | 0.73 | TSHR (0.37) | THRBALDH1A1 | |
| SCHEMBL7160228 | 0.73 | TSHR (0.37) | THRBALDH1A1 | |
| SCHEMBL5605964 | 0.73 | TSHR (0.39) | THRBALDH1A1 | |
| SCHEMBL218320 | 0.73 | THRB (0.46) | THRBTHRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279441-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-4349902-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-11530318-B2 | Rubber composition and pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| CN-111465645-B | Rubber composition and pneumatic tire | 株式会社普利司通 | 2022-11-15 | — | — | CN | disclosed |
| EP-3725836-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2022-08-24 | — | — | EP | disclosed |
| CN-111465645-A | Rubber composition and pneumatic tire | 株式会社普利司通 | 2020-07-28 | — | — | CN | disclosed |
| CN-108602987-B | Rubber composition and tire | 株式会社普利司通 | 2020-07-21 | — | — | CN | disclosed |
| WO-2020054484-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | 株式会社ブリヂストン | 2020-03-19 | — | — | WO | disclosed |
| EP-1818186-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-15 | — | — | EP | disclosed |