Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863877 | 0.79 | MAPT (0.42) | MAPTKLK7HTTSMN1; SMN2MEN1 | |
| SCHEMBL2780133 | 0.77 | THRB (0.51) | THRB | |
| SCHEMBL561301 | 0.75 | TSHR (0.45) | THRBSMN1; SMN2ALDH1A1CYP3A4CTSK | |
| SCHEMBL3765449 | 0.75 | HCAR2 (0.42) | MAPTTHRBHCAR2MEN1KMT2A | |
| SCHEMBL14410617 | 0.73 | MAPT (0.56) | MAPTTGM2THRBHTTSMN1; SMN2 | |
| SCHEMBL5605885 | 0.73 | THRB (0.41) | TGM2THRBHCAR2ALDH1A1 | |
| SCHEMBL28397599 | 0.73 | TDP1 (0.51) | THRBSMN1; SMN2KMT2AALDH1A1LMNA | |
| Acrylic Acid Ethyl Ester SCHEMBL28335812 | 0.73 | GAA (0.47) | MAPTTGM2THRBSMN1; SMN2MEN1 | |
| SCHEMBL28863896 | 0.73 | HCAR2 (0.67) | THRBHCAR2KMT2AALDH1A1CYP3A4 | |
| SCHEMBL41557 | 0.73 | HCAR2 (0.67) | THRBHCAR2KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016976-A2 | HEMOCOMPATIBLE POLYMER SYSTEMS AND RELATED METHODS | ALBRIGHT ROBERT L (US) | 2005-02-24 | — | — | WO | claimed |