SCHEMBL560589

SCHEMBL560589

C=CC(=O)OCCN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 1/20 0.36
ALDH1A1 P00352 3/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MMP1 P03956 3/20 0.33
MMP2 P08253 3/20 0.33
MMP9 P14780 3/20 0.33
MMP8 P22894 3/20 0.33
MMP13 P45452 3/20 0.33
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.33
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7920244 1.00 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9873897 1.00 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL7920243 1.00 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL7906773 0.99 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL30424942 0.92 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL633255 0.91 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9872589 0.90 HPGD (0.32) TSHRHPGDTHRBMMP1MMP2
SCHEMBL31127917 0.90 TSHR (0.46) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL2523004 0.90 TSHR (0.46) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL13198515 0.88 TSHR (0.35) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110291174-B Tackifying proppant for carbon dioxide-based fracturing fluid and preparation and application methods thereof 沙特阿拉伯石油公司 2022-04-26 CN claimed
CN-114024094-A Fluorine-containing lithium ion battery diaphragm and preparation method thereof 山东遥米新能源科技有限公司 2022-02-08 CN claimed
US-10131834-B2 Self-suspending modified proppant system for carbon dioxide based fracturing fluids ARAMCO SERVICES COMPANY 2018-11-20 US claimed
US-10131833-B2 Self-suspending modified proppant system for carbon dioxide based fracturing fluids ARAMCO SERVICES COMPANY (US) 2018-11-20 US claimed
US-10119068-B2 Viscosifying modified proppant system for carbon dioxide based fracturing fluids SAUDI ARABIAN OIL COMPANY (SA) 2018-11-06 US claimed
US-10106733-B2 Viscosifying modified proppant system for carbon dioxide based fracturing fluids SAUDI ARABIAN OIL COMPANY (SA) 2018-10-23 US claimed
US-10066155-B1 Viscosifying proppants for use in carbon dioxide-based fracturing fluids and methods of making and use thereof SAUDI ARABIAN OIL COMPANY (SA) 2018-09-04 US claimed
US-8039093-B2 Method for preparing tamperproof ID documents AGFA-GEVAERT N.V. (BE) 2011-10-18 US claimed
US-20090202838-A1 SELF-ASSEMBLING OPTICAL FILM AND A METHOD OF MANUFACTURING THE SAME ALLIANCE MATERIAL CO., LTD. (TW) 2009-08-13 US claimed
CN-101504467-A Self-structuring optical film structures and methods of making same ALLIANCE MATERIAL CO LTD (CN) 2009-08-12 CN claimed
US-5239026-A Curable fluorinated acrylates, adhesion promoters; silane coupler MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US claimed
US-5232600-A Polymerizing a fluorine containing monomer in the presence of a microporous polymeric membrane substrate forming a permanent chemical, bond between substrate and super strate PALL CORPORATION (US) 1993-08-03 US claimed
EP-0333464-B1 POLYMER CLADDINGS FOR OPTICAL FIBRE WAVEGUIDES MINNESOTA MINING & MFG (US) 1993-05-12 EP claimed
US-5152287-A Cross-linked fluorinated polymers for use in gas sensors CORDIS CORPORATION (US) 1992-10-06 US claimed
US-4968116-A HEAT RESISTANCE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-11-06 US claimed
US-4957982-A PROTECTIVE COATED SURFACES CROWN DECORATIVE PRODUCTS LIMITED (GB) 1990-09-18 US claimed
US-4954256-A BONDING A FLUORINE CONTAINING UNSATURATED MONOMER TO MICROPOROUS MEMBRANE PALL CORPORATION (US) 1990-09-04 US claimed
EP-0333464-A1 Polymer claddings for optical fibre waveguides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-09-20 EP claimed
EP-0307074-A2 Antifouling coating for polymerisation reactors Crown Berger Limited (GB) 1989-03-15 EP claimed
US-4383878-A RELEASE COATING OF RADIATION CURED POLYFLUORINATED ACRYLATE MONOMER, CURING AGENT AND POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-17 US claimed