Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.48 |
| ▸ | TFPI | P10646 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29536066 | 0.94 | GNPAT (0.50) | SIRT5TFPIGNPATKEAP1OPRL1 | |
| SCHEMBL29498977 | 0.93 | TFPI (0.52) | SIRT5TFPIOPRL1IL23R | |
| SCHEMBL12711226 | 0.91 | GNPAT (0.45) | SIRT5TFPIGNPATKEAP1OPRL1 | |
| SCHEMBL29659724 | 0.89 | TFPI (0.49) | SIRT5TFPIGNPATOPRL1IL23R | |
| SCHEMBL19791333 | 0.87 | TFPI (0.41) | SIRT5TFPIOPRL1QRFPRNPY4R | |
| SCHEMBL19791191 | 0.87 | TFPI (0.41) | SIRT5TFPIOPRL1QRFPRNPY4R | |
| SCHEMBL17732656 | 0.87 | GNPAT (0.47) | SIRT5TFPIGNPATNPY4RNPY5R | |
| SCHEMBL26708100 | 0.87 | GNPAT (0.49) | SIRT5TFPIGNPATNPY4RNPY5R | |
| SCHEMBL10532990 | 0.87 | SIRT5 (0.45) | SIRT5TFPIGNPATKEAP1OPRL1 | |
| SCHEMBL12070950 | 0.87 | SIRT5 (0.53) | SIRT5TFPIKEAP1NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567179-A4 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF TUMOR CELL ADHESION, PAIN AND INFLAMMATION | OMEROS CORP (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1567179-A1 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF TUMOR CELL ADHESION, PAIN AND INFLAMMATION | Omeros Corporation (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004043479-A1 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF TUMOR CELL ADHESION, PAIN AND INFLAMMATION | OMEROS CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20030195461-A1 | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation | OMEROS CORPORATION | 2003-10-16 | — | — | US | disclosed |
| US-6492332-B1 | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation | OMEROS CORPORATION | 2002-12-10 | — | — | US | disclosed |