Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.53 |
| ▸ | TFPI | P10646 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 5/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.44 |
| ▸ | NPY1R | P25929 | 4/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 7/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088150 | 0.94 | SIRT5 (0.48) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL20806247 | 0.92 | NPY4R (0.45) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL13701341 | 0.90 | SIRT5 (0.63) | SIRT5NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL12073161 | 0.90 | SIRT5 (0.55) | SIRT5NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL31437196 | 0.89 | TFPI (0.48) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL20783808 | 0.88 | NPY4R (0.45) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL13166808 | 0.87 | SIRT5 (0.59) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL30463273 | 0.87 | SIRT5 (0.59) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL5606014 | 0.87 | SIRT5 (0.48) | SIRT5TFPINPY4RNPY5RNPY1R | |
| SCHEMBL12680257 | 0.86 | RXFP1 (0.47) | SIRT5TFPIIL23RRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130171085-A1 | AMINO ACID DERIVATIVES; COMPOSITIONS CONTAINING THEM; USE AS AGENTS FOR TREATING HUMAN PERSPIRATION | L'OREAL (FR) | 2013-07-04 | — | — | US | disclosed |
| WO-2011157611-A2 | AMINO ACID DERIVATIVES; COMPOSITIONS CONTAINING THEM; USE AS AGENTS FOR TREATING HUMAN PERSPIRATION | L'OREAL (FR) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171085-A1 | AMINO ACID DERIVATIVES; COMPOSITIONS CONTAINING THEM; USE AS AGENTS FOR TREATING HUMAN PERSPIRATION | TYR, CUTA, AADAT | SIRT5 4161/4885TFPI 2403/4885NPY4R 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.