O-Xylene

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	O-Xylene SCHEMBL8717730	1.00	TSHR (0.50)	TSHRACHEALDH1A1KDM4EHPGD
	O-Xylene SCHEMBL29189113	1.00	TSHR (0.50)	TSHRACHEALDH1A1KDM4EHPGD
	O-Xylene SCHEMBL31491254	1.00	TSHR (0.50)	TSHRACHEALDH1A1KDM4EHPGD
	O-Xylene SCHEMBL28201006	0.89	ERCC5 (0.42)	TSHRACHEALDH1A1KDM4EHPGD
	O-Xylene SCHEMBL4671123	0.89	TSHR (0.40)	TSHRACHEALDH1A1KDM4EHPGD
	Orthocresol SCHEMBL17842626	0.87	TRPA1 (0.41)	TSHRALDH1A1KDM4EHPGDERCC5
	Toluene SCHEMBL10539493	0.85	LMNA (0.55)	TSHRACHEALDH1A1KDM4EHPGD
	Toluene SCHEMBL1692174	0.85	LMNA (0.55)	TSHRACHEALDH1A1KDM4EHPGD
	O-Tolylamine SCHEMBL29875684	0.85	TDP1 (0.58)	ALDH1A1KDM4EHPGDERCC5FEN1
	O-Xylene SCHEMBL9693080	0.84	TSHR (0.56)	TSHRACHEALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.