Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.64 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.64 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.64 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.64 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.64 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.64 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.64 |
| ▸ | DRD4 | P21917 | 3/20 | 0.62 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.62 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957930 | 0.87 | SSTR5 (0.72) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27448907 | 0.85 | KMT2A (1.00) | KMT2ADRD4SLC6A12SLC6A13SIGMAR1 | |
| SCHEMBL7224869 | 0.83 | SIGMAR1 (0.77) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31736417 | 0.83 | MCHR1 (0.77) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL694949 | 0.82 | SIGMAR1 (0.82) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5606272 | 0.80 | MEN1 (0.74) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL61848 | 0.80 | TMEM97 (0.83) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5258490 | 0.79 | SMYD3 (0.86) | KMT2AROCK2ROCK1MEN1 | |
| SCHEMBL31555021 | 0.79 | SMYD3 (0.86) | KMT2AROCK2ROCK1MEN1 | |
| SCHEMBL14344796 | 0.79 | KMT2A (0.72) | KMT2APRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |