Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.75 |
| ▸ | DRD4 | P21917 | 6/20 | 0.74 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.69 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.66 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694949 | 0.87 | SIGMAR1 (0.82) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL8706202 | 0.87 | DRD4 (0.87) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL7224869 | 0.86 | SIGMAR1 (0.77) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL31736417 | 0.86 | MCHR1 (0.77) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL7218037 | 0.86 | SIGMAR1 (1.00) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL5606683 | 0.85 | KMT2A (0.74) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL9593089 | 0.84 | DRD4 (0.79) | KMT2ASIGMAR1DRD4SLC6A12DRD2 | |
| SCHEMBL14344796 | 0.84 | KMT2A (0.72) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL61848 | 0.82 | TMEM97 (0.83) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 | |
| SCHEMBL17946338 | 0.82 | KMT2A (0.80) | KMT2ASIGMAR1DRD4SLC6A12SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138458-A | Treatment and prevention of prostatic cancer | LILLY CO ELI (US) | 1996-12-25 | — | — | CN | disclosed |