SCHEMBL5607017

SCHEMBL5607017

COc1ccccc1C(C)(O)C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
TP53 P04637 2/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 2/20 0.43
CASR P41180 1/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TLR2 O60603 1/20 0.41
ERN1 O75460 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41
ATM Q13315 2/20 0.40
MAPT P10636 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5550397 0.81 CA1 (0.46) GAACA1CA2TP53TSHR
SCHEMBL30039266 0.79 CA1 (0.44) GAACA1CA2TP53TSHR
SCHEMBL21033760 0.79 CA1 (0.44) GAACA1CA2TP53TSHR
SCHEMBL29472193 0.78 CA1 (0.52) GAACA1CA2TP53TSHR
SCHEMBL9326049 0.78 CASR (0.57) GAACA1CA2TP53TSHR
SCHEMBL2951312 0.78 CA1 (0.52) GAACA1CA2TP53TSHR
SCHEMBL3364583 0.77 CA1 (0.46) GAACA1CA2TP53TSHR
SCHEMBL8784494 0.76 CA1 (0.55) GAACA1CA2TP53TSHR
SCHEMBL131681 0.75 GABRA1 (0.41) GAACA2TSHRALDH1A1CASR
SCHEMBL3205223 0.75 CASR (0.50) GAACA1CA2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1857477-A1 (METH)ACRYLATE COMPOUND, PROCESS FOR PRODUCTION OF THE COMPOUND, (METH)ACRYLATE COPOLYMER, PROCESS FOR PRODUCTION OF THE COPOLYMER, AND SOFT INTRAOCULAR LENS HOYA CORPORATION (JP) 2007-11-21 EP disclosed