SCHEMBL3364583

SCHEMBL3364583

COc1ccccc1C(Br)(Br)C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TLR2 O60603 1/20 0.43
ERN1 O75460 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43
NFE2L2 Q16236 4/20 0.42
TFEB P19484 1/20 0.42
GAA P10253 2/20 0.41
MAOB P27338 1/20 0.41
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5550397 0.80 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL21175581 0.80 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL3366374 0.79 IRAK4 (0.42) CA1CA2CA7CA9GAA
SCHEMBL3362504 0.79 ALDH1A1 (0.44) GAAALDH1A1KDM4ELMNACYP1A2
SCHEMBL21033760 0.78 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL30039266 0.78 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL3117896 0.78 TLR2 (0.48) CA1CA2CA7CA9CA12
SCHEMBL5607017 0.77 GAA (0.45) CA1CA2CA7CA9CA12
SCHEMBL3362514 0.77 LMNA (0.56) TLR2GAAALDH1A1LMNACYP1A2
SCHEMBL3362138 0.77 ALDH1A1 (0.50) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed