Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607569 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL5606513 | 0.84 | TP53 (0.42) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL29615749 | 0.77 | TP53 (0.44) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL21248100 | 0.75 | TP53 (0.42) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL6907503 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9715903 | 0.72 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL28846228 | 0.72 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL29871077 | 0.72 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL9715865 | 0.72 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL7134946 | 0.72 | TP53 (0.42) | TP53TDP1ALDH1A1TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169874-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-7138440-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-11-21 | — | — | US | disclosed |
| US-7101949-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-09-05 | — | — | US | disclosed |
| US-7091299-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-08-15 | — | — | US | disclosed |
| US-6908978-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2005-06-21 | — | — | US | disclosed |
| US-20050131191-A1 | High refractive index polymeric siloxysilane compositions | SALAMONE JOSEPH C (US) | 2005-06-16 | — | — | US | disclosed |
| US-20050127557-A1 | High refractive index polymeric siloxysilane compositions | SOLTA MEDICAL, INC. | 2005-06-16 | — | — | US | disclosed |
| US-20050131189-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, LTD. | 2005-06-16 | — | — | US | disclosed |
| EP-1465903-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-1448572-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20030109661-A1 | High refractive index polymeric siloxysilane compositions | BAUSCH HEALTH US, LLC | 2003-06-12 | — | — | US | disclosed |
| US-20030100697-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003040157-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040158-A1 | HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |