Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607068 | 0.84 | TP53 (0.37) | ALDH1A1TSHR | |
| SCHEMBL1398313 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRPOLB | |
| SCHEMBL6907503 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL5080699 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL25266761 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL1405992 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRPOLBCA1CA2 | |
| SCHEMBL31494226 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL31494218 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL7134965 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TSHRPOLB | |
| SCHEMBL5958178 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169874-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-7138440-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-11-21 | — | — | US | disclosed |
| US-7101949-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-09-05 | — | — | US | disclosed |
| US-7091299-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2006-08-15 | — | — | US | disclosed |
| US-6908978-B2 | High refractive index polymeric siloxysilane compositions | BAUSCH & LOMB INCORPORATED (US) | 2005-06-21 | — | — | US | disclosed |
| US-20050131191-A1 | High refractive index polymeric siloxysilane compositions | SALAMONE JOSEPH C (US) | 2005-06-16 | — | — | US | disclosed |
| US-20050127557-A1 | High refractive index polymeric siloxysilane compositions | SOLTA MEDICAL, INC. | 2005-06-16 | — | — | US | disclosed |
| US-20050131189-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, LTD. | 2005-06-16 | — | — | US | disclosed |
| US-20030109661-A1 | High refractive index polymeric siloxysilane compositions | BAUSCH HEALTH US, LLC | 2003-06-12 | — | — | US | disclosed |
| US-20030100697-A1 | High refractive index polymeric siloxysilane compositions | SALIX PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |