Fluoride Ion

Fluoride Ion

SCHEMBL5607074

Cc1cccc(CC2=C([Zr+2]C3=C(Cc4cccc(C)c4)C=CC3)CC=C2)c1.[F-].[F-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HRH3 Q9Y5N1 3/20 0.39
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
IDO1 P14902 2/20 0.37
DAO P14920 1/20 0.36
TACR1 P25103 2/20 0.35
HTR6 P50406 1/20 0.34
MPO P05164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL1131269 0.80 CALM1 (0.39) HTR2CHTR2BTAAR1
Fluoride Ion SCHEMBL5165586 0.80 TAAR1 (0.39) POLBMEN1KMT2AHRH3HTR2C
SCHEMBL3837763 0.77 CALM1 (0.39) HTR2CHTR2BTAAR1
Fluoride SCHEMBL5165597 0.77 TAAR1 (0.39) POLBMEN1KMT2AHRH3HTR2C
SCHEMBL1263547 0.70 TAAR1 (0.60) HRH3TAAR1IDO1DAO
SCHEMBL30000562 0.70 TAAR1 (0.60) HRH3TAAR1IDO1DAO
SCHEMBL29459538 0.70 TAAR1 (0.60) HRH3TAAR1IDO1DAO
Hydrochloric Acid SCHEMBL5608728 0.69 KMT2A (0.39) MEN1KMT2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL10323201 0.68 TAAR1 (0.39) POLBMEN1KMT2AHRH3HTR2C
Hydrochloric Acid SCHEMBL3683524 0.68 CALM1 (0.31) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673400-A4 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2007-07-11 EP disclosed
EP-1673400-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES Univation Technologies, LLC (US) 2006-06-28 EP disclosed
WO-2005044863-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECHNOLOGIES, LLC (US) 2005-05-19 WO disclosed