Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5608728

Cc1ccccc1CC1=C([Zr+2]C2=C(Cc3ccccc3C)C=CC2)CC=C1.[Cl-].[Cl-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.34
SLC6A2 known ✓ P23975 1/20 0.33
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
CYP2A13 Q16696 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A4 P31645 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10323047 0.69 TAAR1 (0.35) KMT2AMEN1SMN1; SMN2LMNAMAPT
Fluoride Ion SCHEMBL5607074 0.69 POLB (0.39) KMT2AMEN1TAAR1HTR2CHTR2B
SCHEMBL29477327 0.67 TAAR1 (0.56) KMT2ALMNACYP2A13TAAR1ACHE
SCHEMBL2090458 0.67 TAAR1 (0.56) KMT2ALMNACYP2A13TAAR1ACHE
Hydrochloric Acid SCHEMBL12814638 0.67 ESR1 (0.33)
Hydrochloric Acid SCHEMBL7551923 0.66 SIGMAR1 (0.41)
SCHEMBL11200954 0.65 TAAR1 (0.54) KMT2ALMNACYP2A13TAAR1ACHE
SCHEMBL29772212 0.65 TAAR1 (0.54) KMT2AMEN1LMNACYP2A13TAAR1
Bromide SCHEMBL6209363 0.65
SCHEMBL3844192 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016689-B1 Olefin thermoplastic elastomer compositions MITSUI CHEMICALS INC (JP) 2007-03-07 EP disclosed
EP-1057867-B1 RESIN DISPERSION, METHOD OF PREPARING THE SAME, RESIN-COATED METAL SHEET OBTAINED WITH THE SAME, AND PROCESS FOR PRODUCING LAMINATE MITSUI CHEMICALS INC (JP) 2005-04-20 EP disclosed
US-6833045-B1 Solid particles of graft modified ethylene/ alpha -olefin copolymer dispersed in solvent; adhesive for packaging; coatings, primers MITSUI CHEMICALS, INC. (JP) 2004-12-21 US disclosed
EP-0754731-B2 Polyamide resin composition MITSUI CHEMICALS INC (JP) 2004-12-15 EP disclosed
EP-0924223-B1 Catalyst component, catalyst and process for ethylenically unsaturated monomer polymerization MITSUI CHEMICALS INC (JP) 2004-05-19 EP disclosed
US-6723794-B2 TO PROVIDE MOLDED PRODUCTS HAVING EXCELLENT TENSILE STRENGTH, ELONGATION AT BREAK AND ELASTOMERIC PROPERTIES MITSUI CHEMICALS, INC. (JP) 2004-04-20 US disclosed
EP-0751182-B1 Olefin thermoplastic elastomer compositions MITSUI CHEMICALS INC (JP) 2003-10-01 EP disclosed
US-20030096912-A1 To provide molded products having excellent tensile strength, elongation at break and elastomeric properties MITSUI CHEMICALS, INC. (JP) 2003-05-22 US disclosed
US-6444603-B1 CATALYST COMPONENT OBTAINED BY REACTING COMPOUND COMPRISING METAL OF GROUP 13 OF PERIODIC TABLE, COMPOUND CAPABLE OF BEING BONDED TO TWO OR MORE OF GROUP 13 METAL, COMPOUND CAPABLE OF FORMING IONIZING IONIC COMPOUND WITH GROUP 13 COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-09-03 US disclosed
US-6414088-B1 SOFT RESIN COMPOSITION COMPRISING POLYETHYLENE RESIN AND LINEAR ETHYLENE/ALPHA-OLEFIN RANDOM COPOLYMER, EACH HAVING SPECIFIED PROPERTIES MITSUI CHEMICALS INC (JP) 2002-07-02 US disclosed
EP-0791627-A1 RESIN COMPOSITION AND USE THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-27 EP disclosed
EP-0754731-A2 Polyamide resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-22 EP disclosed
EP-0751182-A1 Olefin thermoplastic elastomer compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-02 EP disclosed
EP-0751156-A2 Ethylene copolymer rubber, vulcanizable rubber composition containing the copolymer rubber, and process for preparing the copolymer rubber MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-02 EP disclosed
US-5567777-A CONTAINING AN ALPHA-OLEFIN; TRANSPARENCY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
US-5567776-A BLEND ELASTOMERIC COPOLYMERS CONTAINING ALPHA- AND CYCLO-OLEFINS; IMPACT STRENGTH, TRANSPARENCY, FIBER OPTICS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
EP-0691354-A1 Unsaturated copolymer of ethylene and process for preparing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-01-10 EP disclosed
US-5470919-A Seals with ozone resistance, heat aging resistance, oil resistance and weatherproofing MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-11-28 US disclosed
EP-0638594-A1 Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-02-15 EP disclosed
EP-0597119-A1 CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-18 EP disclosed