Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606929 | 0.82 | MAPT (0.50) | LMNAMAPTHPGD | |
| SCHEMBL3191344 | 0.82 | KMT2A (0.40) | KMT2A | |
| SCHEMBL2371418 | 0.81 | KDM4E (0.41) | — | |
| SCHEMBL3197090 | 0.81 | NPC1 (0.40) | MAPTHTTMAPK1 | |
| SCHEMBL3209282 | 0.79 | TTR (0.55) | — | |
| SCHEMBL5607782 | 0.79 | POLB (0.40) | MAPTHPGDKMT2A | |
| SCHEMBL3201503 | 0.78 | HSD17B14 (0.38) | — | |
| SCHEMBL3190028 | 0.78 | — | — | |
| SCHEMBL3198719 | 0.78 | ALDH1A1 (0.49) | HPGDALDH1A1TDP1 | |
| SCHEMBL3197931 | 0.78 | TTR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845087-A1 | Hydroxyphenyl derivatives and biological applications thereof | Mutabilis SA (FR) | 2007-10-17 | — | — | EP | disclosed |
| EP-1845087-A1 | Hydroxyphenyl derivatives and biological applications thereof | Mutabilis SA (FR) | 2007-10-17 | — | — | EP | disclosed |