Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733355 | 0.95 | PKM (0.48) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 | |
| SCHEMBL5607856 | 0.95 | PKM (0.43) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 | |
| SCHEMBL5080859 | 0.88 | PKM (0.52) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 | |
| SCHEMBL2745710 | 0.85 | PKM (0.56) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 | |
| SCHEMBL13738157 | 0.85 | — | — | |
| SCHEMBL5607861 | 0.85 | GRM1 (0.42) | GRM1FFAR3 | |
| SCHEMBL6226927 | 0.85 | PKM (0.35) | PKMRAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5614131 | 0.83 | PKM (0.54) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 | |
| SCHEMBL5607460 | 0.83 | GRM1 (0.41) | GRM1 | |
| SCHEMBL301039 | 0.83 | PKM (0.59) | PKMRAB9ASMN1; SMN2ALDH1A1GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |