Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924557 | 0.85 | MEN1 (0.44) | MEN1KMT2AGAANPSR1THRB | |
| SCHEMBL5608660 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAANPSR1THRB | |
| SCHEMBL5608324 | 0.84 | MEN1 (0.45) | MEN1KMT2AGAANPSR1THRB | |
| SCHEMBL27560710 | 0.83 | DPP4 (0.42) | MEN1KMT2AGAANPSR1DPP4 | |
| SCHEMBL5607877 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2AGAANPSR1DPP4 | |
| SCHEMBL5608309 | 0.81 | DPP4 (0.43) | GAANPSR1DPP4THRBALDH1A1 | |
| SCHEMBL6058712 | 0.81 | MEN1 (0.59) | MEN1KMT2AGAANPSR1THRB | |
| SCHEMBL1696546 | 0.79 | THRB (0.41) | NPSR1DPP4THRBALDH1A1LMNA | |
| SCHEMBL21467414 | 0.78 | NPSR1 (0.39) | MEN1KMT2AGAANPSR1DPP4 | |
| SCHEMBL18924643 | 0.77 | NPSR1 (0.48) | MEN1KMT2ANPSR1DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |