Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696549 | 0.93 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL25499083 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL5608223 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRGAA | |
| SCHEMBL15449151 | 0.86 | PKM (0.48) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL21262868 | 0.86 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL18469153 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRGAATHRB | |
| SCHEMBL21470449 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRGAATHRB | |
| SCHEMBL5608031 | 0.84 | NPSR1 (0.39) | ALDH1A1TSHRGAATHRB | |
| SCHEMBL5608620 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL29757005 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |