Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602546 | 1.00 | TSHR (0.47) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL6058547 | 0.88 | EPHX1 (0.53) | TSHREPHX1ALDH1A1EPHX2GAA | |
| SCHEMBL2851919 | 0.83 | ALDH1A1 (0.47) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL5608356 | 0.83 | EPHX1 (0.44) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL7636763 | 0.83 | EPHX1 (0.44) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL12783362 | 0.83 | TSHR (0.43) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL5608094 | 0.82 | ALDH1A1 (0.47) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL6531345 | 0.81 | ALDH1A1 (0.46) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL31144035 | 0.81 | ALDH1A1 (0.46) | TSHREPHX1ALDH1A1EPHX2MDH1 | |
| SCHEMBL4975642 | 0.81 | TSHR (0.70) | TSHREPHX1EPHX2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | claimed |
| CN-112250594-B | Method for preparing 3-acetamido-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-112694410-A | 3-amino-1-adamantanol and synthesis method thereof | 广东仁康达材料科技有限公司 | 2021-04-23 | — | — | CN | claimed |
| CN-112250594-A | Method for preparing 3-acetamido-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2021-01-22 | — | — | CN | claimed |
| JP-11106360-A | — | — | None | — | — | JP | disclosed |
| CN-116444438-B | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2024-02-13 | — | — | CN | disclosed |
| CN-116924918-B | Preparation method of 3-amino-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116924918-A | Preparation method of 3-amino-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | disclosed |
| CN-112250594-B | Method for preparing 3-acetamido-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-112250594-B | Method for preparing 3-acetamido-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-112250594-B | Method for preparing 3-acetamido-1-adamantanol | 浙江荣耀生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| EP-0915077-B1 | POLYMERIZABLE ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAICEL CHEM (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6235851-B1 | ESTERIFICATION OR AMIDATION REACTION OF AN ADAMANTANE DERIVATIVE; GROUP 3A METAL CATALYST | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0915077-A1 | POLYMERIZABLE ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Daicel Chemical Industries, Ltd. (JP) | 1999-05-12 | — | — | EP | disclosed |
| JP-H11106360-A | ADAMANTANE DERIVATIVE AND ITS PRODUCTION | DAICEL CHEM IND LTD | 1999-04-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DPP4, DPP7, DPP3 | TSHR 451/4885EPHX1 4094/4885ALDH1A1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.