Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MDH1 | P40925 | 1/20 | 0.41 |
| ▸ | MDH2 | P40926 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851919 | 0.83 | ALDH1A1 (0.47) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL29602546 | 0.81 | TSHR (0.47) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL5608005 | 0.81 | TSHR (0.47) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL31144035 | 0.81 | ALDH1A1 (0.46) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL12783361 | 0.81 | ALDH1A1 (0.43) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL771405 | 0.80 | EPHX2 (0.67) | ALDH1A1EPHX2EPHX1 | |
| SCHEMBL12783362 | 0.80 | TSHR (0.43) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL5608094 | 0.79 | ALDH1A1 (0.47) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL13647390 | 0.77 | EPHX2 (0.47) | ALDH1A1EPHX2EPHX1TSHRDPP4 | |
| SCHEMBL16301140 | 0.77 | DPP4 (0.43) | ALDH1A1EPHX2EPHX1TSHRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117861-A1 | USE OF ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-12-15 | — | — | WO | claimed |