Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775097 | 0.86 | LCK (0.56) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL243781 | 0.84 | SCD (0.61) | SCDGAACHRM4CXCR4MAOB | |
| SCHEMBL3579989 | 0.78 | SCD (0.64) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL3589249 | 0.78 | SCD (0.62) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3581698 | 0.77 | RAB9A (0.69) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL3587287 | 0.77 | SCD (0.65) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL3585444 | 0.77 | KDM4E (0.63) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL14871550 | 0.77 | SCD (0.61) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL3577784 | 0.76 | SCD (0.67) | SCDNPC1RAB9AGAAMEN1 | |
| SCHEMBL4030640 | 0.76 | SMN1; SMN2 (0.54) | SCDKMT2ACHRM4CXCR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758564-A2 | SYNERGISTIC METHODS AND COMPOSITIONS FOR TREATING CANCER | Brystol-Myers Squibb Company (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005094376-A2 | SYNERGISTIC METHODS AND COMPOSITIONS FOR TREATING CANCER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-10-13 | — | — | WO | disclosed |