Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.68 |
| ▸ | ITGAV | P06756 | 2/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.67 |
| ▸ | TPH1 | P17752 | 3/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608052 | 1.00 | ITGB3 (0.68) | ITGB3ITGAVITGA2BNR1H4TPH1 | |
| SCHEMBL14381168 | 0.88 | NR1H4 (0.64) | ITGB3ITGAVITGA2BNR1H4TPH1 | |
| SCHEMBL19234470 | 0.88 | ITGB3 (0.67) | ITGB3ITGAVITGA2BTPH1SLC7A5 | |
| SCHEMBL7769029 | 0.88 | ITGB3 (0.67) | ITGB3ITGAVITGA2BTPH1SLC7A5 | |
| SCHEMBL757263 | 0.88 | ITGB3 (0.67) | ITGB3ITGAVITGA2BTPH1SLC7A5 | |
| SCHEMBL5607035 | 0.85 | EPHX2 (0.68) | NR1H4TPH1SLC7A5ALPIPKM | |
| SCHEMBL5607824 | 0.85 | ITGB3 (0.68) | ITGB3ITGAVITGA2BSLC7A5ITGB1 | |
| SCHEMBL5607029 | 0.85 | EPHX2 (0.68) | NR1H4TPH1SLC7A5ALPIPKM | |
| SCHEMBL5607830 | 0.85 | ITGB3 (0.68) | ITGB3ITGAVITGA2BSLC7A5ITGB1 | |
| SCHEMBL28241907 | 0.84 | NR1H4 (0.77) | NR1H4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY | 2007-10-11 | — | — | US | claimed |
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | GLP1R, GIPR, IAPP | ITGB3 4608/4885ITGAV 4301/4885ITGA2B 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.