SCHEMBL757263

SCHEMBL757263

N[C@@H](Cc1ccc(NC(=O)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.67
ITGAV P06756 1/20 0.67
ITGA2B P08514 1/20 0.67
SLC7A5 Q01650 3/20 0.62
ALPI P09923 1/20 0.62
PKM P14618 1/20 0.62
PTGS1 P23219 1/20 0.62
XIAP P98170 1/20 0.62
PTPN1 P18031 3/20 0.56
MMP9 P14780 1/20 0.55
TPH1 P17752 1/20 0.55
CACNA1B Q00975 1/20 0.55
APBA1 Q02410 1/20 0.55
KDM4E B2RXH2 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
SIRT1 Q96EB6 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7769029 1.00 ITGB3 (0.67) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL19234470 1.00 ITGB3 (0.67) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL21690098 0.94 SLC7A5 (0.62) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL14381168 0.92 NR1H4 (0.64) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL5608045 0.88 ITGB3 (0.68) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL5608052 0.88 ITGB3 (0.68) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL6251223 0.87 KMT2A (0.58) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL19234474 0.87 MITF (0.59) ITGB3ITGAVITGA2BPTPN1TPH1
SCHEMBL19234475 0.87 ITGB3 (0.57) ITGB3ITGAVITGA2BSLC7A5ALPI
SCHEMBL19234472 0.87 ITGB3 (0.57) ITGB3ITGAVITGA2BSLC7A5ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615855-A2 NEW ANTIBACTERIAL PRODUCTS University of Liverpool (GB) 2025-09-17 EP disclosed
WO-2024100391-A2 NEW ANTIBACTERIAL PRODUCTS UNIVERSITY OF LIVERPOOL (GB) 2024-05-16 WO disclosed
EP-3578566-B1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON VERTA RES PRODUCTION COMPANY LTD (RU) 2023-07-19 EP disclosed
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2022-04-14 US disclosed
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 US disclosed
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2019-02-07 US disclosed
WO-2017136943-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2017-08-17 WO disclosed
EP-1532262-B1 PEPTIDE AMIDATION PROCESS MEDTRONIC INC (US) 2013-07-10 EP disclosed
US-8288130-B2 Polypeptide cleavage process MEDTRONIC, INC. (US) 2012-10-16 US disclosed
EP-1532142-B1 POLYPEPTIDE CLEAVAGE PROCESS MEDTRONIC INC (US) 2012-03-21 EP disclosed
US-20050227313-A1 Polypeptide cleavage process MEDTRONIC, INC. 2005-10-13 US disclosed
EP-1532142-A2 POLYPEPTIDE CLEAVAGE PROCESS Restoragen, Inc. (US) 2005-05-25 EP disclosed
EP-1532262-A2 PETIDE AMIDATION PROCESS Restoragen, Inc. (US) 2005-05-25 EP disclosed
EP-1531836-A2 POLYPEPTIDE CLEAVAGE PROCESS Restoragen, Inc. (US) 2005-05-25 EP disclosed
WO-2004011599-A2 POLYPEPTIDE CLEAVAGE PROCESS RESTORAGEN, INC. (US) 2004-02-05 WO disclosed
WO-2003099853-A2 PETIDE AMIDATION PROCESS RESTORAGEN, INC. (US) 2003-12-04 WO disclosed
WO-2003099852-A2 PEPTIDE DERIVATIZATION PROCESS RESTORAGEN INC. (US) 2003-12-04 WO disclosed
WO-2003100015-A2 POLYPEPTIDE CLEAVAGE PROCESS RESTORAGEN, INC. (US) 2003-12-04 WO disclosed
JP-2001163802-A 4-BENZOYLAMINOPHENYLALANINE DERIVATIVE SANKYO CO LTD 2001-06-19 JP disclosed
US-6197794-B1 ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES CELLTECH THERAPEUTICS LIMITED (GB) 2001-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 ITGB3 4181/4885ITGAV 4218/4885ITGA2B 4143/4885
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 ITGB3 4129/4885ITGAV 4173/4885ITGA2B 4089/4885
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 ITGB3 4181/4885ITGAV 4218/4885ITGA2B 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.