Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL15136032 | 1.00 | DAO (0.47) | DAOTSHRNAPRTLMNASMN1; SMN2 | |
| Benzoic Acid SCHEMBL28119539 | 0.94 | DAO (0.41) | DAOTSHRNAPRTLMNASMN1; SMN2 | |
| Benzoic Acid SCHEMBL569362 | 0.91 | TSHR (0.52) | DAOTSHRNAPRTLMNACES2 | |
| Benzoic Acid SCHEMBL569388 | 0.90 | DAO (0.44) | DAOTSHRNAPRTLMNAPOLB | |
| Benzoic Acid SCHEMBL569372 | 0.89 | ALDH1A1 (0.45) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL571002 | 0.88 | ALDH1A1 (0.47) | TSHRCES2CES1ALDH1A1PLA2G4B | |
| Benzoic Acid SCHEMBL30822815 | 0.88 | TSHR (0.56) | DAOTSHRNAPRTLMNACES2 | |
| Benzoic Acid SCHEMBL28366021 | 0.87 | DAO (0.44) | DAOTSHRNAPRTLMNASMN1; SMN2 | |
| Benzoic Acid SCHEMBL28797334 | 0.87 | DAO (0.44) | DAOTSHRNAPRTLMNASMN1; SMN2 | |
| Benzoic Acid SCHEMBL27851821 | 0.87 | DAO (0.44) | DAOTSHRNAPRTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924549-A | Ziegler-Natta catalyst component, process for preparing the same, olefin polymerization catalyst and process for polymerizing olefin | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-114437264-B | Low-VOC low-odor polypropylene resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114456289-B | Titanium-containing catalyst, catalyst for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-114456288-B | Titanium-containing catalyst, catalyst for olefin polymerization reaction, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-116769090-A | Preparation method of butene-1 polymer | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769096-A | Preparation method of high isotactic polybutene-1 | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769083-A | Preparation method and device of 1-butene polymer | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769091-A | Preparation method of polybutene-1 resin | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769088-A | Preparation method of high isotactic polybutene-1 | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769089-A | Preparation process and device of polybutene-1 resin | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-103012625-B | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2015-03-11 | — | — | CN | claimed |
| CN-103012632-B | Preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2015-03-11 | — | — | CN | claimed |
| CN-103012627-B | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2015-03-11 | — | — | CN | claimed |
| CN-102453147-B | Catalyst component, catalyst and method for olefin polymerization | CHINA PETROLEUM & CHEMICAL | 2013-06-05 | — | — | CN | claimed |
| CN-102453149-B | Olefin polymerization catalyst component, olefin polymerization catalyst and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-06-05 | — | — | CN | claimed |
| CN-103012631-A | Preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012632-A | Preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012627-A | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012625-A | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012626-A | Olefin polymerization catalyst ingredient, preparation method of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |