Benzoic Acid

Benzoic Acid

SCHEMBL571002

CCCCCCC(O)CC(C)O.O=C(O)c1ccccc1.O=C(O)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
PLA2G4B P0C869 1/20 0.47
GPR84 Q9NQS5 4/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
FFAR1 O14842 1/20 0.45
NAAA Q02083 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
CNR2 P34972 1/20 0.43
RARB P10826 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL569372 0.98 ALDH1A1 (0.45) ALDH1A1PLA2G4BGPR84CES2CES1
Benzoic Acid SCHEMBL569388 0.94 DAO (0.44) ALDH1A1PLA2G4BCES2CES1TSHR
Benzoic Acid SCHEMBL569738 0.91 PLA2G4B (0.48) PLA2G4BGPR84CES2CES1FFAR4
Benzoic Acid SCHEMBL10946836 0.89 FFAR4 (0.56) ALDH1A1PLA2G4BGPR84CES2CES1
Benzoic Acid SCHEMBL27846691 0.89 FFAR4 (0.56) ALDH1A1PLA2G4BGPR84CES2CES1
Benzoic Acid SCHEMBL28711585 0.89 FFAR4 (0.56) ALDH1A1PLA2G4BGPR84CES2CES1
Benzoic Acid SCHEMBL15136032 0.88 DAO (0.47) ALDH1A1PLA2G4BCES2CES1TSHR
Benzoic Acid SCHEMBL560823 0.88 DAO (0.47) ALDH1A1PLA2G4BCES2CES1TSHR
Benzoic Acid SCHEMBL28285786 0.87 RARB (0.45) ALDH1A1PLA2G4BGPR84CES2CES1
Benzoic Acid SCHEMBL569810 0.86 TSHR (0.48) PLA2G4BCES2CES1NAAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397658-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS Braskem America, Inc. (US) 2018-11-07 EP disclosed
EP-3397657-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS Braskem America, Inc. (US) 2018-11-07 EP disclosed
EP-3397659-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS Braskem America, Inc. (US) 2018-11-07 EP disclosed
WO-2017117433-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO disclosed
WO-2017117439-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO disclosed
WO-2017117443-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO disclosed
EP-2601224-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2013-06-12 EP disclosed
WO-2012017040-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-02-09 WO disclosed