Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634113 | 0.96 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBPKMATMHSD17B10 | |
| SCHEMBL5608308 | 0.91 | POLB (0.42) | SMN1; SMN2POLBATMHSD17B10OPRM1 | |
| SCHEMBL5608170 | 0.89 | POLB (0.41) | SMN1; SMN2POLBATMHSD17B10OPRM1 | |
| SCHEMBL25831437 | 0.89 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBPKMATMHSD17B10 | |
| SCHEMBL11102433 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBPKMATMHSD17B10 | |
| SCHEMBL5608040 | 0.79 | TSHR (0.41) | SMN1; SMN2PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL5608256 | 0.78 | MEN1 (0.40) | SMN1; SMN2POLBTSHRALDH1A1MEN1 | |
| SCHEMBL4036133 | 0.76 | TSHR (0.44) | SMN1; SMN2PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL5608366 | 0.76 | TSHR (0.41) | SMN1; SMN2PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL17048689 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBPKMATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |