Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797401 | 0.89 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL5608188 | 0.89 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HSD11B1NPSR1LMNA | |
| SCHEMBL5608088 | 0.89 | NPSR1 (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL7735490 | 0.84 | NPSR1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL16708397 | 0.83 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4033960 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5608298 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL8197101 | 0.78 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2HSD11B1MAPT | |
| SCHEMBL5608323 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5608428 | 0.78 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2HSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |