Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | GLMN | Q92990 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607499 | 0.89 | DPP4 (0.47) | RXFP1TSHREPHX1KMT2ADPP4 | |
| SCHEMBL5608031 | 0.85 | NPSR1 (0.39) | TSHREPHX1NPC1LMNAHTT | |
| SCHEMBL6560659 | 0.84 | TSHR (0.39) | RXFP1TSHREPHX1KMT2ADPP4 | |
| SCHEMBL6560094 | 0.82 | TSHR (0.38) | RXFP1TSHREPHX1KMT2ADPP4 | |
| SCHEMBL18469162 | 0.82 | DPP4 (0.41) | TSHREPHX1DPP4ALDH1A1 | |
| SCHEMBL1696580 | 0.82 | DPP4 (0.41) | TSHREPHX1DPP4ALDH1A1 | |
| SCHEMBL6058547 | 0.81 | EPHX1 (0.53) | RXFP1TSHREPHX1KMT2ANPC1 | |
| SCHEMBL5608375 | 0.79 | PKM (0.39) | TSHRDPP4ALDH1A1DPP8DPP9 | |
| SCHEMBL6252048 | 0.79 | TSHR (0.45) | RXFP1TSHREPHX1KMT2ANPC1 | |
| SCHEMBL15449150 | 0.79 | TSHR (0.45) | TSHREPHX2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |