SCHEMBL5608348

SCHEMBL5608348

CC(=O)NC12CC3(O)CC(O)(CC(O)(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CA2 P00918 1/20 0.30
PTGS1 P23219 1/20 0.30
MMP12 P39900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608231 0.95 EPHX1 (0.31) EPHX1KDM4ECA2PTGS1MMP12
SCHEMBL5608449 0.89 GAA (0.38)
SCHEMBL5608314 0.85 GAA (0.38)
SCHEMBL1074030 0.85 GAA (0.41)
SCHEMBL16118629 0.84 KDM4E (0.37) EPHX1KDM4ECA2PTGS1MMP12
SCHEMBL11224012 0.84 KDM4E (0.37) EPHX1KDM4ECA2PTGS1MMP12
SCHEMBL23863822 0.81
SCHEMBL19766594 0.81
SCHEMBL5608356 0.79 EPHX1 (0.44) EPHX1
SCHEMBL1733449 0.78 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39744-E1 Adamantane derivatives and process for producing them DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-24 US disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed