Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608554 | 1.00 | IDO1 (0.56) | IDO1L3MBTL1MAPTATMPOLB | |
| SCHEMBL5608495 | 0.87 | FPR2 (0.62) | L3MBTL1MAPTATMPOLBTHRB | |
| SCHEMBL5608490 | 0.87 | FPR2 (0.62) | L3MBTL1MAPTATMPOLBTHRB | |
| SCHEMBL27880853 | 0.85 | ATM (0.60) | L3MBTL1ATMPOLBTHRBALDH1A1 | |
| SCHEMBL30436738 | 0.82 | ATM (0.51) | ATMPOLBTHRBALDH1A1CYP2C9 | |
| SCHEMBL5608758 | 0.80 | ATM (0.62) | L3MBTL1ATMPOLBTHRBALDH1A1 | |
| SCHEMBL5608756 | 0.80 | ATM (0.62) | L3MBTL1ATMPOLBTHRBALDH1A1 | |
| SCHEMBL2830729 | 0.79 | ATM (0.53) | ATMPOLBTHRBALDH1A1CYP2C9 | |
| SCHEMBL2830730 | 0.79 | ATM (0.53) | ATMPOLBTHRBALDH1A1CYP2C9 | |
| SCHEMBL16899832 | 0.78 | HDAC1 (0.55) | L3MBTL1ATMPOLBTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |