Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.31 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2356961 | 1.00 | ACHE (0.35) | ACHEBACE1CCR5PTGS2ALOX5 | |
| Hydrochloric Acid SCHEMBL2357164 | 0.98 | ACHE (0.33) | ACHEBACE1 | |
| Hydrochloric Acid SCHEMBL673240 | 0.93 | — | — | |
| Bromide SCHEMBL28417717 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL1071263 | 0.79 | — | — | |
| SCHEMBL17233532 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2354174 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27808711 | 0.77 | ACHE (0.36) | ACHEBACE1CCR5PTGS2ALOX5 | |
| Trifluoromethanesulfonic Acid SCHEMBL628926 | 0.76 | KCNH2 (0.39) | ACHEKCNH2 | |
| Hydrochloric Acid SCHEMBL7201381 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016689-B1 | Olefin thermoplastic elastomer compositions | MITSUI CHEMICALS INC (JP) | 2007-03-07 | — | — | EP | disclosed |
| EP-1057867-B1 | RESIN DISPERSION, METHOD OF PREPARING THE SAME, RESIN-COATED METAL SHEET OBTAINED WITH THE SAME, AND PROCESS FOR PRODUCING LAMINATE | MITSUI CHEMICALS INC (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-6833045-B1 | Solid particles of graft modified ethylene/ alpha -olefin copolymer dispersed in solvent; adhesive for packaging; coatings, primers | MITSUI CHEMICALS, INC. (JP) | 2004-12-21 | — | — | US | disclosed |
| EP-0754731-B2 | Polyamide resin composition | MITSUI CHEMICALS INC (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6723794-B2 | TO PROVIDE MOLDED PRODUCTS HAVING EXCELLENT TENSILE STRENGTH, ELONGATION AT BREAK AND ELASTOMERIC PROPERTIES | MITSUI CHEMICALS, INC. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-0751182-B1 | Olefin thermoplastic elastomer compositions | MITSUI CHEMICALS INC (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-20030096912-A1 | To provide molded products having excellent tensile strength, elongation at break and elastomeric properties | MITSUI CHEMICALS, INC. (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6414088-B1 | SOFT RESIN COMPOSITION COMPRISING POLYETHYLENE RESIN AND LINEAR ETHYLENE/ALPHA-OLEFIN RANDOM COPOLYMER, EACH HAVING SPECIFIED PROPERTIES | MITSUI CHEMICALS INC (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-0754731-B1 | Polyamide resin composition | MITSUI CHEMICALS INC (JP) | 2002-03-20 | — | — | EP | disclosed |
| EP-0751156-B1 | Ethylene copolymer rubber, vulcanizable rubber composition containing the copolymer rubber, and process for preparing the copolymer rubber | MITSUI CHEMICALS INC (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5837791-A | WITH ANOTHER ALPHA-OLEFIN AND AT LEAST ONE NONCONJUGATED TRIENE OR TETRAENE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-17 | — | — | US | disclosed |
| US-5698651-A | RANDOM COPOLYMER OF ETHYLENE, ALPHA-OLEFIN, NONCONJUGATED POLYENES POLYMERIZABLE BY METALLOCENE CATALYST; MOLDABILITY, HIGH STRENGTH, LOW TEMPERATURE FLEXIBILITY, THERMAL AGING RESISTANCE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0801047-A1 | NORBORNENE COMPOUNDS HAVING CHAIN POLYENE GROUPS AND UNSATURATED ETHYLENIC COPOLYMER PRODUCED WITH THE USE OF THE SAME | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0791627-A1 | RESIN COMPOSITION AND USE THEREOF | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0754731-A2 | Polyamide resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0751182-A1 | Olefin thermoplastic elastomer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751156-A2 | Ethylene copolymer rubber, vulcanizable rubber composition containing the copolymer rubber, and process for preparing the copolymer rubber | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0691354-A1 | Unsaturated copolymer of ethylene and process for preparing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5470919-A | Seals with ozone resistance, heat aging resistance, oil resistance and weatherproofing | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0638594-A1 | Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |