Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | RARG | P13631 | 3/20 | 0.34 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29160570 | 0.90 | POLB (0.36) | ALDH1A1TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL8927511 | 0.84 | GABRA1 (0.35) | ALDH1A1MAPK1HMGCRRXRAPPARG | |
| SCHEMBL31127742 | 0.83 | RXRA (0.34) | HMGCRRXRAPPARGRARGRARA | |
| SCHEMBL3281055 | 0.82 | POLB (0.33) | ALDH1A1TSHRTDP1RXRAPPARG | |
| SCHEMBL16301296 | 0.78 | CYP1A2 (0.36) | TSHRTDP1CYP3A4MAPK1CYP1A2 | |
| SCHEMBL3635251 | 0.78 | NR5A2 (0.31) | HMGCRRXRAPPARGRARGNR5A2 | |
| SCHEMBL2690018 | 0.78 | HMGCR (0.41) | TSHRHMGCRRXRAPPARGRARG | |
| SCHEMBL31049510 | 0.77 | HMGCR (0.35) | ALDH1A1TSHRTDP1CYP3A4MAPK1 | |
| SCHEMBL12020484 | 0.77 | HMGCR (0.40) | TSHRHMGCRRXRAPPARGRARG | |
| SCHEMBL29150410 | 0.77 | CYP1A2 (0.45) | TDP1RXRACYP1A2CYP2C19RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412412-B1 | MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS | BAYER MATERIALSCIENCE AG (DE) | 2007-02-21 | — | — | EP | disclosed |
| EP-1412412-A2 | MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS | Bayer MaterialScience AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-20030013788-A1 | Melt polycarbonate with improved resistance to hydrolysis | BAYER AKTIENGESELLSCHAF (DE) | 2003-01-16 | — | — | US | disclosed |
| WO-2002077101-A2 | MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |